10. Comparison of The Efficacy of Artesunate-Amodiaquine with Quinine-Clindamycin for Treatment of Uncomplicated Falciparum Malaria in Children

Malaria has been a scourge of mankind
for centuries. 1 Malaria (mala means
bad and aria means air) 2 is an acute and
chronic protozoan illness characterized
by paroxysms of fever, chills, sweats, fatigue, anemia,
and splenomegaly.3 Malaria is a major communicable
disease of the tropics and subtropics, killing more than
one million people each year,4 and is undergoing a
resurgence in areas where it was previously controlled.5
This disease is distributed throughout tropical
countries but its incidence is lower in dry climates and
at high altitudes.6 Results from malariometric survey
showed high parasite rates (parasite rates of more than
2%) in endemic malaria in Sumatra Utara Province
from 1989 until 1993.8
Chloroquine-resistant strains of P falciparum
have been reported from many areas of the world,
i.e., Indian subcontinent, Southeast Asia, Oceania,
Panama, and South America and from extensive
areas of East Africa. If chloroquine-resistance is.......

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10. Comparison of The Efficacy of Artesunate-Amodiaquine with Quinine-Clindamycin for Treatment of Uncomplicated Falciparum Malaria in Children